January 15, 2010

Hologic to Release First Quarter Fiscal 2010 Operating Results on Monday, February 1, 2010

BEDFORD, Mass., (January 15, 2010) - Hologic, Inc. (Hologic or the Company) (NASDAQ:
HOLX), a leading developer, manufacturer and supplier of premium diagnostics, medical
imaging systems and surgical products dedicated to serving the healthcare needs of women, today
announced plans to release its first quarter fiscal 2010 operating results on Monday,
February 1, 2010 after market close. In conjunction with the release, management will host a
conference call on Monday, February 1, 2010, at 5:00 p.m. (EST).

Interested participants may listen to the call by dialing 877-856-1965 or 719-325-4894 for
international callers and referencing code 4933598 approximately 15 minutes prior to the call on
February 1st. For those unable to participate in the live broadcast, a replay will be available one
hour after the call ends through Friday, February 19, 2010, at 888-203-1112 or 719-457-0820 for
international callers, access code 4933598.

The Company will also provide a live webcast of the call. Interested participants may access the
webcast on the Company's website at www.hologic.com. A replay of the call will be archived on
the Company's website.

About Hologic, Inc.
Hologic, Inc. is a leading developer, manufacturer and supplier of premium diagnostics products,
medical imaging systems and surgical products dedicated to serving the healthcare needs of
women. Hologic's core business units are focused on breast health, diagnostics, GYN surgical,
and skeletal health. Hologic provides a comprehensive suite of technologies with products for
mammography and breast biopsy, radiation treatment for early-stage breast cancer, cervical
cancer screening, treatment for menorrhagia, permanent contraception, osteoporosis assessment,
preterm birth risk assessment, mini C-arm for extremity imaging and molecular diagnostic
products including reagents for a variety of DNA and RNA analysis applications. For more
information, visit www.hologic.com.

Contact:
Deborah R. Gordon
Vice President, Investor Relations
Hologic, Inc.
deborah.gordon@hologic.com
Tel: 781.999.7716




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