For Immediate Release - November 22, 2005

Hologic, Inc. to Host Investor Reception at the RSNA Trade Show

BEDFORD, Mass. (November 22, 2005) - Hologic, Inc. (NASDAQ: HOLX), a leading provider of specialized medical imaging equipment for women's health and state-of-the-art digital imaging systems, today announced the Company will host a meeting for members of the investment community who will be attending the RSNA (Radiological Society of North America ) trade show in Chicago.

This meeting will be held on Tuesday, November 29, 2005, at McCormick Place from 8:00 - 10:00 AM (Central Time) and will include a presentation by members of Hologic's management team.

Interested participants may listen to the call (listen mode only) by dialing 800-769-8320 at 7:50 AM (Central Time) and referencing the Hologic Investor Meeting. This call is expected to last approximately thirty minutes. For those unable to participate in the live broadcast, a replay will be available one hour after the call ends through December 12, 2005 at 888-509-0081.

The Company will also provide a live webcast of the call. Interested participants may access the webcast at the Company's website at www.hologic.com. A replay of the call will be archived on the Company's website.

Hologic, Inc. is a leading developer, manufacturer and supplier of medical imaging systems dedicated to serving the healthcare needs of women, and a leading developer of state-of-the-art digital imaging technology for general radiography and mammography applications. Hologic's resources are focused on developing systems with superior image quality and diagnostic accuracy while providing exemplary customer service. This focus has enabled the Company to capture significant market share in its core niches against large, multinational companies, while engendering customer loyalty. Hologic's core business units are focused on osteoporosis assessment, mammography and breast biopsy, direct-to-digital X-ray for general radiography applications and mini C-arm imaging for orthopedic applications. Hologic's product lines are premier brands in their markets and command leading market positions.


Contact:
Glenn Muir   Frances Crecco
Executive Vice President, Finance   Director, Investor Relations
Hologic, Inc.   Hologic, Inc.
Tel: 781.999.7300   Tel: 781.999.7377

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