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Panther system

Experience freedom and control over your molecular testing workflow like never before with the Panther system from Hologic. This fully automated platform provides test consolidation, random-access sample loading and proven assay chemistry to deliver high performance and results you can trust.


The Panther system provides unprecedented control of workflow, driven by random access and continuous loading of molecular samples, reagents and consumables. This innovative design enables your lab to improve productivity and accelerate results, ultimately helping to enhance patient care and reduce lab costs.


Created to be a fully automated sample-to-result instrument, the Panther system eliminates the need for batch processing and automates all aspects of nucleic acid testing on a single, integrated platform. This system combines true walkaway freedom with intuitive design for ease of use. With its extraordinary level of automation, the Panther system improves laboratory productivity and operational efficiencies, promising to transform the world of molecular testing as we know it today.



The Panther system provides unique, innovative and streamlined features.


The only system that gives you control to run the following:

  • Samples as you choose with random access or batching
  • Multiple assays on the same patient sample
  • Up to 4 different assays simultaneously on a single platform 

Integrated automation, enabling you to maximize productivity and reduce costs with

  • True walkaway freedom and sample-to-answer automation
  • The ability to run multiple tests from a single sample, anytime
  • Bi-directional LIS interface for streamlined data management
  • Automated scheduled maintenance, reducing hands-on time

Frees your lab from the confines of batch testing with

  • Random access and continuous sample/reagent loading to enable flexible workflow
  • Load-and-go with unattended results processing
  • Auto-reflexing for HPV genotyping
  • Controls or calibrators that are run only once in 24 hours

Have confidence in your results with

  • Sample chain-of-custody control (PosID)
  • In-process checks, which reduce operator and system errors
  • Liquid-level detection and reagent dispense verification
  • Contamination control
  • Quality control (Levey-Jennings and prevalence) reporting

Assays are currently available on the Panther system globally, including US, Canada and EU. Please see your local sales rep or distributor to confirm availability in other countries.

FDA Approved/Cleared/EUA
  • Aptima Combo 2® Assay for CT/NG
  • Aptima® Trichomonas vaginalis Assay
  • Aptima® HSV 1 & 2 Assay
  • Aptima® HPV Assay
  • Aptima® HPV 16 18/45 Genotype Assay
  • Aptima® Zika Virus Assay*
  • Aptima® HIV-1 Quant Assay
  • Aptima® HCV Quant Dx Assay
* The Aptima Zika Virus assay:
  • This test has not been FDA cleared or approved;
  • This test has been authorized by FDA under an EUA for use by authorized laboratories;
  • This test has been authorized only for the detection of RNA from Zika virus and diagnosis of Zika virus infection, not for any other viruses or pathogens; and
  • This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of in vitro diagnostic tests for detection of Zika virus and/or diagnosis of Zika virus infection undersection 564(b)(1) of the Act, 21 U.S.C.§ 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner.
CE Marked
  • Aptima Combo 2® Assay for CT/NG
  • Aptima® Chlamydia trachomatis Assay
  • Aptima® Neisseria gonorrhoeae Assay
  • Aptima® Trichomonas vaginalis Assay
  • Aptima® HPV Assay
  • Aptima® HPV 16 18/45 Genotype Assay
  • Aptima® Mycoplasma genitalium Assay
  • Aptima® HIV-1 Quant Dx Assay
  • Aptima® HCV Quant Dx Assay
  • Aptima® HBV Quant Assay
  • Aptima® HSV 1 & 2 Assay
In Development
  • HBV
  • Bacterial vaginosis
  • Candida vaginalis
  • Mycoplasma genitalium

In development for the US, already CE marked.

  • TMA assays: 3.5 hrs to first result; up to 275 samples processed in 8 hrs.
  • RT-TMA assays: 2.7 hrs to first result; up to 320 samples processed in 8 hrs; up to 750 samples processed in 15.2 hrs

Sample Capacity

  • 120 sample tubes in 8 racks with continuous access

Waste Capacity

  • Can process up to 750 tests before unloading waste

Component Dimensions (w x d x h)

  • Panther system     

122 cm (48 in) x 81.5 cm (32 in) x 175 cm (69 in)

  • UPS (optional) 

21.4 cm (8.4 in) x 41.0 cm (16.1 in) x 32.5 cm (12.8 in)


  • Panther system     

363 kg (800 lbs)

  • UPS (optional) 

34.5 kg (76 lbs)

Sample Tube Barcode Types

  • Code 39, Code 93, Code 128 (ISBT 128), Interleaved 2 of 5, JAN 13, NW7, UPC, and Codabar.

Environmental Requirements

  • Ambient temperature    

15°C - 30°C

  • Relative humidity

20% - 85%

Electrical Requirements

  • Electrical input 

100-240 +/- 10% VAC , 50-60 Hz, single phase

  • Current input     

Minimum of 15-amp circuit (dedicated); 20-amp circuit (dedicated) if used with optional UPS

  • Current draw 

Instrument and ancillaries draw 700 W average in power-save mode to 1400 W peak
- 100 VAC circuit draws 13 amps
- 240 VAC circuit draws 5.4 amps

System Output

  • Heat dissipation

550 watts (1878 BTU/hour) during steady state

  • Drain output

None: waste fluids drain to removable containers

Performance Data

The Panther system can process up to 320 real-time TMA or 275 tests per 8-hour shift, and up to 750 tests in 16 hours. To provide maximum flexibility and menu expansion, the system has been designed for both end-point and real-time assays. The reaction tube takes approximately 3.5 hours to journey through the system for endpoint assays, and approximately 2.7 hours for real-time assays, before a result is produced. Every 5 minutes, 5 additional tests are completed. With its impressive level of automation, the design should help improve the efficiency of a typical 8-hour workday, with up to 4 hours of result processing labor-free. The Panther system will continue generating results unattended, providing the maximized productivity that molecular labs need.



PANTHER - The next step in the evolution of molecular diagnostics

Fluid Management
Fluid Management
Internal Modules
Internal Modules
Loading MTUs
Loading MTUs
Waste Management
Waste Management
Load Reagents
Load Reagents
Positive Sample ID
Positive Sample ID
TCR Addition
TCR Addition
Liquid Level Sensing
Liquid Level Sensing
TC Hybridization
TC Hybridization
Transcription Mediated Amplification (TMA)
Transcription Mediated Amplification (TMA)
Probe and Selection Reagent Addition
Probe and Selection Reagent Addition
Reagent Dispense Verification
Reagent Dispense Verification
Sequence Detection
Sequence Detection
Penetrable Cap Technology
Penetrable Cap Technology