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Patients Deserve Accurate Vaginitis Testing

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Vaginitis is a Leading Reason for OBGYN Visits1

Most women experience an episode of vaginitis at least once in their lifetime.2

Better Vaginitis Testing for the Win

Aptima® vaginitis assays deliver highly sensitive detection across multiple targets.

Molecular nucleic acid amplification tests (NAATs) can detect 3x more mixed infections than clinical diagnosis with wet mount, culture, and Amsel’s criteria.8

Centers for Disease Control and Prevention (CDC) and ACOG recommend NAATs for detection of TV.9,10

 

Quiz Results

Enhance your understanding and gain valuable insights by taking our quiz to learn about the benefits of NAAT testing, the overlapping symptoms of STIs and vaginitis, and the complexities of co-infections.

Take Our Quiz

Question 1 of 3

True or False: NAAT and traditional testing methods are equivalent in sensitivity and specificity for vaginitis detection.

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ANSWER: B. NAAT is highly sensitive, often detecting 3-5x more TV infections than wet-mount microscopy and 3x more co-infection cases than clinical diagnosis with wet mount, culture, and Amsel’s criteria (CDC, Schwebke)
Next
  1. Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, Reno H, Zenilman JM, Bolan GA. Sexually Transmitted Infections Treatment Guidelines, 2021. CDC MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1. PMID: 34292926; PMCID: PMC8344968.
  2. Schwebke JR, Gaydos CA, Nyirjesy P, Paradis S, Kodsi S, Cooper CK. Diagnostic Performance of a Molecular Test versus Clinician Assessment of Vaginitis. J Clin Microbiol. 2018 May 25;56(6):e00252-18. doi: 10.1128/JCM.00252-18. PMID: 29643195; PMCID: PMC5971525.
  3. Sobel JD, Subramanian C, Foxman B, Fairfax M, Gygax SE. Mixed vaginitis-more than coinfection and with therapeutic implications. Curr Infect Dis Rep. 2013 Apr;15(2):104-8. doi: 10.1007/s11908-013-0325-5. PMID: 23354954

Question 2 of 3

What infections share overlapping symptoms with vaginitis?

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ANSWER: D. All of these infections can present with similar symptoms, making testing key for helping diagnose patients accurately and provide the treatment they need.
Next
  1. Kent H. Epidemiology of vaginitis. Am J Obstet Gynecol. 1991;165(4):1168-1176.
  2. Manhart LE, Gaydos CA, Taylor SN, Lillis RA, Hook EW 3rd, Klausner JD, Remillard CV, Love M, McKinney B, Getman DK. Characteristics of Mycoplasma genitalium Urogenital Infections in a Diverse Patient Sample from the United States: Results from the Aptima Mycoplasma genitalium Evaluation Study (AMES). J Clin Microbiol. 2020 Jun 24;58(7):e00165-20. doi: 10.1128/JCM.00165-20. PMID: 32321783; PMCID: PMC7315021.
  3. Hainer BL, Gibson MV. Vaginitis. Am Fam Physician. 2011 Apr 1;83(7):807-15. PMID: 21524046. 5. Bautista CT, Wurapa EK, Sateren WB, Morris SM, Hollingsworth BP, Sanchez JL. Association of Bacterial Vaginosis With Chlamydia and Gonorrhea Among Women in the U.S. Army. Am J Prev Med. 2017 May;52(5):632-639. doi: 10.1016/j.amepre.2016.09.016.
  4. CDC. Bacterial Vaginosis Fact Sheet. Center for Disease Control and Prevention website. Last reviewed February 15, 2023. Accessed February 15, 2023. https://www.cdc.gov/std/bv/stdfact-bacterial-vaginosis.htm
  5. CDC. Chlamydia Fact Sheet. Center for Disease Control and Prevention website. Last reviewed February 15, 2023. Accessed February 15, 2023. https://www.cdc.gov/std/chlamydia/stdfact-chlamydia.htm 10. CDC. Gonorrhea – CDC Detailed Fact Sheet. Center for Disease Control and Prevention website. Last reviewed April 11, 2023. Accessed July 11, 2023. https://www.cdc.gov/std/gonorrhea/stdfact-gonorrhea-detailed.htm
  6. CDC. Mycoplasma genitalium – CDC Detailed Fact Sheet. Center for Disease Control and Prevention website. Last reviewed December 5, 2022. Accessed June 1, 2023. https://www.cdc.gov/std/mgen/stdfact-Mgen-detailed.htm.

Question 3 of 3

How many women who present with vaginitis have at least one STI?

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ANSWER: B. ~1 in 5. Recent data show that 18.5% of women presenting with vaginitis symptoms have at least one STI.
Next
  1. Schwebke J, et al. Results from a Multi-Center U.S. Clinical Study using STI Nucleic Acid Amplification Testing. J. Clin. Microbiol., 2024. a Hologic sponsored study.

 

You are in the know! You answered correctly to most or all of the questions.
 

You’re well on your way! Continue reading about Vaginitis! You’ll feel more informed and empowered when speaking with your healthcare provider.

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Revolutionizing Vaginitis Detection

Discover how our innovative FDA-cleared NAATs transform vaginitis detection empowering healthcare providers and labs to deliver accurate, efficient care.

Doctor and patient reviewing lab tests

Get patients back to everyday life by accurately detecting vaginitis objectively and comprehensively.

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Lab technician viewing test results

Automate your facility’s molecular testing workflows while instilling confidence in your testing results.

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    References
    1. Kent HL. Epidemiology of Vaginitis. Am J Obstet Gynecol. 1991 Oct;165(4 Pt 2):1168-76. 2. Workowski, et al. Sexually Transmitted Infections Treatment Guidelines 2021. MMWR Recomm Rep 2021;70. 3. Koumans EH. The Prevalence of Bacterial Vaginosis in the United States, 2001-2004; Associations with Symptoms, Sexual Behaviors, and Reproductive Health. 4. CDC Bacterial Vaginosis (BV) Statistics. Last updated February 10, 2020. Accessed January 24, 2024. https://www.cdc.gov/std/bv/stats.html 5. Paladine HL. Vaginitis: Diagnosis and Treatment. Am Fam Physician. Am Fam Physician. 2018 Mar 1;97(5):321-329. 6. Anderson MR, Klink K, Cohrssen A. Evaluation of vaginal complaints. JAMA .2004;291(11):1368–1379. doi:10.1001/jama.291.11.1368. 7. Hainer BL, Gibson MV. Vaginitis. Am Fam Physician. 2011 Apr 1;83(7):807-15. PMID: 21524046. 8. Schwebke JR, Gaydos CA, Nyirjesy P, et al. Diagnostic performance of a molecular test versus clinician assessment of vaginitis. J Clin Microbiol. 2018;56. doi:10.1128/JCM.00252.